In vivo nano-biosensing element of red blood cell-mediated delivery

Biosensors based on nanotechnology are developing rapidly and widely applied in many fields including biomedicine, environmental monitoring, national defense analytical chemistry, have achieved vital positions these fields. Novel nano-materials intensively developed manufactured for potential biosensing theranostic applications while lacking comprehensive assessment of their health risks. The integration diagnostic vivo biosensors the DDSs delivery therapeutic drugs holds an enormous next-generation platforms. Controllable, precise, safe devices agents to target tissues, organs, or cells is important determinant advanced nanobiosensor-based Particularly, inspired by biological investigations red blood (RBCs), strategies RBC-mediated been currently different stages transforming from research design pre-clinical clinical investigations. In this review, nanobiosensors bio-imaging at single-cell level, medical diagnostics, detection biomolecules cellular activities presented. A perspective technical framework state-of-the-art systems explained detail inspire implementation platforms taking advantage RBC-delivery modalities.